Maria’s skin tears open every day but, though her body is fragile, her will is formidable

Eleven-year-old Maria Alejandra is a force to be reckoned with. Strong-willed, articulate and wise beyond her years, she knows what she wants, and sometimes that’s to stay home from school. Because she suffers from epidermolysis bullosa, a rare disease that causes her fragile skin to blister and tear, it’s easy to sympathise when even the most mundane tasks are a painful struggle. It’s also easy to sympathise with her mother who worries that, if Maria doesn’t continue doing everyday things with her peers, she could end up always indoors and isolated.

Deeply honest and compassionate, In Crystal Skin is imbued with the hope and hardship that characterise the daily routines of Maria and her family. This short version is part of a larger feature film that chronicles the lives of Maria and three other people in Colombia’s capital Bogotá who are living with epidermolysis bullosa, a disease for which there is currently no treatment or cure.

The meanings and mysteries of the iconic Sutton Hoo helmet brought vividly to life

The early Anglo-Saxon artefact known as the Sutton Hoo helmet has, since its origins in the 7th century, passed through many incarnations, including: exquisite armour, long-dormant burial object, astounding archeological discovery and high-stakes puzzle. Today, the Sutton Hoo helmet – so named for the site in the English county of Suffolk at which it was discovered in 1939 – lives on as one of the British Museum’s most famous pieces. In this video, Sue Brunning, curator of the museum’s European Early Medieval Insular Collection, examines the iconic object, revealing the multitude of meanings and mysteries it holds. Through her investigation, Brunning brilliantly captures how history is an ever-fluid work in progress, being made and remade as new discoveries are brought – often quite literally – to light.

When medicine offers no relief, a biohacker begins a radical self-experiment

In 2015, the US scientist, artist and self-described ‘biohacker’ Josiah Zayner undertook a controversial project to help resolve his lifelong gastrointestinal issues. The plan was to replace the vast colonies of microbiota on and inside his body via transplants from a healthy donor – and then document the proceedings. Although an accomplished biologist with a PhD in biophysics and two years as a NASA researcher under his belt, Zayner’s endeavour was frowned upon by much of the scientific community, with critics condemning the project for operating outside the normal boundaries of bioethics. Especially controversial was Zayner’s plan to self-administer a faecal transplant – a risky procedure usually reserved for potentially fatal conditions. In their documentary Gut Hack, the filmmakers Mario Furloni and Kate McLean follow Zayner’s fascinating, radical and not-for-the-squeamish quest for relief. In so doing, they also confront deeper issues of ethics and autonomy at the core of contemporary science.

Against ‘beauty’ in science – how striving for elegance stifles progress

That there is an inherent ‘beauty’ and ‘elegance’ to the laws of nature is a view that permeates the field of physics. But, according to the German theoretical physicist Sabine Hossenfelder, the notion that the further you peer into reality, the easier the equation gets, has no basis in reality. Indeed, since the mid-20th-century, the maths of physics has become increasingly knotty, even as many physicists have continued to search for a path back to simplicity. In this interview with Robert Lawrence Kuhn for the PBS series Closer to Truth, Hossenfelder makes the case that this fixation on beauty isn’t just misguided – it’s stifling scientific progress.

Sitting by the fire with a nomadic tribe, a physicist ponders the many shapes of wisdom

The Italian theoretical physicist Carlo Rovelli is a pioneer in the field of quantum gravity, and often thought of as one of the world’s foremost scientific thinkers. In this brief animation by James Siewert, which features narration from the Swazi-English actor Richard E Grant, Rovelli recalls communing with members of the Hadza tribe of northern Tanzania – one of the last hunter-gatherer societies on Earth. Sitting by the fire, thoughts of the peculiar trajectory of Homo sapiens and the many shapes of human wisdom flicker in his head, as he ponders the gaps, large and small, between his world and theirs.