A veteran returns to war through virtual reality, hoping to be rid of his PTSD

Almost 40 years after post-traumatic stress disorder (PTSD) was officially recognised as a distinct mental condition, treating its frequently debilitating symptoms has proven extremely challenging to sufferers and clinicians. The human brain is hard-wired to defend against threats, making little distinction between real and perceived danger. However, Merel Kindt, a professor of clinical psychology at the University of Amsterdam, believes that she has discovered a breakthrough treatment for overactive fear responses. By first exposing patients to their greatest fears and then administering a beta-blocker called propranolol, Kindt says that fear memories can be overwritten and made benign.

This is the second instalment of the US director Lana Wilson’s four-part documentary series A Cure for Fear, which follows patients undergoing this potentially revolutionary treatment. It features Kindt attempting to alleviate the PTSD symptoms of a Canadian veteran of the war in Afghanistan: to trigger the fear memory, he must relive his most traumatic battle experience in harrowing detail via an immersive VR recreation. Watch the first instalment of the series here.

The uncanny art inspired by evolution and generated by ‘crossbreeding’ images

When viewing the work of the US artist and tool developer Joel Simon, you might find that his images are unlike anything you’ve ever seen before – which makes sense, as they weren’t quite born of nature or a human mind. Inspired by the biological properties of evolution and emergence, Simon uses simple programming rules, which, when applied over and over, give rise to uncanny images that augment the human imagination. His most recent work, explored in this video from Science Friday, applies a machine-learning framework known as a generative adversarial network (GAN) to two images. Guided by human users via Simon’s website Artbreeder, his programs ‘crossbreed’ pictures of everything from animals to artworks. Fascinating digital artefacts in their own right, the resulting, author-less images raise complex questions at the nexus of art, programming and design.

From imbalanced humours to brain chemistry – on the evolution of melancholy

The Ancient Greeks blamed sadness on bodily humours called ‘melaina kole’ (black bile). Today, clinical depression is often understood as an imbalance of brain chemicals – although this is a paradigm that many experts believe is overdue for an update. This animation from TED-Ed offers a brief examination of the history of melancholy, scoping how philosophers, poets, writers and scientists have envisioned and altered our understanding of the experience across the ages.

The meanings and mysteries of the iconic Sutton Hoo helmet brought vividly to life

The early Anglo-Saxon artefact known as the Sutton Hoo helmet has, since its origins in the 7th century, passed through many incarnations, including: exquisite armour, long-dormant burial object, astounding archeological discovery and high-stakes puzzle. Today, the Sutton Hoo helmet – so named for the site in the English county of Suffolk at which it was discovered in 1939 – lives on as one of the British Museum’s most famous pieces. In this video, Sue Brunning, curator of the museum’s European Early Medieval Insular Collection, examines the iconic object, revealing the multitude of meanings and mysteries it holds. Through her investigation, Brunning brilliantly captures how history is an ever-fluid work in progress, being made and remade as new discoveries are brought – often quite literally – to light.

When medicine offers no relief, a biohacker begins a radical self-experiment

In 2015, the US scientist, artist and self-described ‘biohacker’ Josiah Zayner undertook a controversial project to help resolve his lifelong gastrointestinal issues. The plan was to replace the vast colonies of microbiota on and inside his body via transplants from a healthy donor – and then document the proceedings. Although an accomplished biologist with a PhD in biophysics and two years as a NASA researcher under his belt, Zayner’s endeavour was frowned upon by much of the scientific community, with critics condemning the project for operating outside the normal boundaries of bioethics. Especially controversial was Zayner’s plan to self-administer a faecal transplant – a risky procedure usually reserved for potentially fatal conditions. In their documentary Gut Hack, the filmmakers Mario Furloni and Kate McLean follow Zayner’s fascinating, radical and not-for-the-squeamish quest for relief. In so doing, they also confront deeper issues of ethics and autonomy at the core of contemporary science.