The Ancient Greeks blamed sadness on bodily humours called ‘melaina kole’ (black bile). Today, clinical depression is often understood as an imbalance of brain chemicals – although this is a paradigm that many experts believe is overdue for an update. This animation from TED-Ed offers a brief examination of the history of melancholy, scoping how philosophers, poets, writers and scientists have envisioned and altered our understanding of the experience across the ages.
From imbalanced humours to brain chemistry – on the evolution of melancholy

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