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If trauma can be passed down, could new therapies blunt the transgenerational impact?

Growing up in a household where her biological parents provided foster care to kids in need, Bianca Jones Marlin was greatly affected by the stories of trauma that her siblings would share. Those childhood experiences, combined with a passion for science, inspires her work as a postdoctoral researcher at the Zuckerman Institute at Columbia University in New York. Through experiments with mice, Jones Marlin studies how trauma affects transgenerational epigenetic inheritance – or, more plainly, how the stress of traumatic experiences and environments can be passed down by parents to their future offspring, even when the stressors occur before pregnancy. And while making scientific leaps from mice to humans is always perilous, Jones Marlin’s research has proved promising, showing that stressors associated with certain odours in parents seem to make their pups more sensitive to those same smells. Ultimately, Jones Marlin hopes that her work can be used to help create therapies to improve outcomes for children who might be affected by transgenerational trauma.

Video by Science Friday

Director: Chelsea Fiske

Producer: Luke Groskin

17 November 2020

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